Pharmacometrics involves the development and application of mathematical models, informed by knowledge on pharmacology, physiology and the disease process, to characterize the interactions between drugs and patients. It is applied to studying pharmacokinetics, pharmacodynamics and disease progression. The ethical necessity to study drugs in the populations where they are to be used is increasingly recognized. To maximize the value of clinical data, study design and analysis must be appropriate. Historically, many datasets have been sent from African countries to better-resourced settings for analysis, but in recent years, it has been demonstrated that capacity can be built and sustained within low- and middle-income countries (LMIC)1 We report the establishment of the Ugandan Chapter of Pharmacometrics Africa, to share learning with other countries seeking to build similar capabilities.
