Tag: PBPK

Registration now open: Physiologically Based Pharmacokinetic (PBPK) Modelling and its Applications in Maternal and Child Health

25 August 2026

Open in-person SymposiumDate: Wednesday, 28th October 2026 Venue: Biomedical Research Institute, Stellenbosch University, Cape Town, South Africa Bringing together researchers, clinicians, pharmacometricians, regulators, and industry partners to advance physiologically based pharmacokinetic (PBPK) modelling in maternal and child health across Africa. Attend a free in-person symposium exploring priorities for integrating PBPK modelling into research, clinical trials, and medicine development. Everyone with an interest in PBPK modelling and maternal and child health is welcome. Places are limited — secure your place early. For admin enquiries please contact kelly.turton@certara.com or veshni@sun.ac.za 29-30 October – Hands-on Simcyp Workshop Participate in an interactive Simcyp training workshop led by Certara. These sessions are intended for students and participants who already have access to Simcyp software. The workshop will focus on building practical PBPK modelling skills while collaboratively developing a regional capacity-building framework and roadmap for model-informed drug development across sub-Saharan Africa.

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Upcoming Workshop: PBPK and QSP Modeling on OSP Suite V12 with Dr Stephan Schaller

14 July 2025

Date:🗓️ Tuesday 23 July, 13:00–17:00🗓️ Wednesday 24 July, 09:00–16:00📍 IDM Training Room, University of Cape Town, Faculty of Health Sciences About the speakerDr Stephan Schaller is the CEO of ESQlabs, a German-based consultancy specializing in physiologically-based pharmacokinetic (PBPK) and quantitative systems pharmacology (QSP) modeling. A leading figure in the development and application of the Open Systems Pharmacology (OSP) platform, Dr Schaller has led numerous training workshops across the globe and actively contributes to making PBPK and QSP modelling more transparent, reproducible, and accessible. About the workshopThis 1.5-day hands-on training will introduce key PBPK modelling principles using PK-Sim, followed by advanced model management using MoBi’s new modularization features in OSP Suite V12. Participants will gain practical experience in: Who should attend?Whether you are a beginner curious about PBPK modelling or an experienced modeler looking to explore the latest OSP Suite updates, this workshop is designed for: Cost: R319.00💸 The workshop includes catering and access to all training materials. Seats are limited – register early to secure your spot! https://shop.esqlabs.com/products/workshop-cape-town 🧠 About this seriesHosted by the PMXAfrica UCT Chapter, this event is part of our ongoing effort to share knowledge, present advances, and discuss best practices in pharmacometrics. We aim to highlight locally-relevant case studies and expand access to high-quality training in model-informed drug development.

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Uganda Chapter Webinar: Understanding ADME Using Physiologically Based Pharmacokinetic Modelling

16 June 2025

24 June 20254:00 PM – 5:00 PM EAT (1h) About the speaker Dr. Ian Haworth is Vice Chair of the Department of Pharmacology and Pharmaceutical Sciences at the Mann USC School of Pharmacy and Pharmaceutical Sciences. He received his PhD in Physical Organic Chemistry from the University of Liverpool, UK, and then spent three years as a Postdoctoral Fellow at the University of Oxford, UK, before joining USC in 1992. Dr. Haworth has a major role in teaching of medicinal chemistry and biopharmaceutics in the PharmD, PhD and Masters programs at USC, and he has lectured and taught courses on this content worldwide. Dr. Haworth’s research work lies at the interface of chemistry, biochemistry, and computational research in pharmacodynamics and pharmacokinetics. This work involves development and utilization of algorithms for prediction of ligand-protein interactions, coupled with methodology for pharmacokinetic simulations. Dr. Haworth’s laboratory has published over 100 scientific articles on this work. Current projects include examining the relationship of affinity with solvation at drug- protein interfaces; exploration of parameters used in PBPK modeling; and use of molecular informatics and AI for prediction of molecular properties. About this series Sharing knowledge, presenting advances and discussing best practices in pharmacometrics, featuring locally-relevant case studies in application of PBPK and pop-PK Who should attend: Anyone interested in learning how pharmacometrics helps to enable safe and effective use of medication Cost: Totally Free –

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PMX Africa Nigeria Chapter announces new monthly webinar series – register today!

13 March 2025

March 2025 Edition Introduction to PBPK and Population Pharmacokinetics Date: Wednesday, March 26, 2025Time: 2 pm WAT Join us for an insightful session on Pharmacokinetic Modeling, where we’ll explore the fundamentals of PBPK and Population Pharmacokinetics. This webinar will cover key differences between these modelling approaches, their applications in drug development and clinical research, and how they enhance our understanding of drug behaviour in diverse populations. About this SeriesThe Pharmacometrics Africa (Nigeria Chapter) Webinar Series is designed to provide a structured learning experience on PBPK and Population Pharmacokinetics. The series will guide participants through fundamental concepts, model development, and real-world applications. Who Should Attend?Anyone interested in learning the fundamentals of pharmacometrics and its application in medication therapy: Academics, Researchers, Postgraduate students, and Undergraduate students. About the Speaker Babajide ShenkoyaBabajide holds a Bachelor of Pharmacy degree and a Master’s in Pharmaceutical Chemistry from Obafemi Awolowo University, where he focused on statistical and computational methods at the Translational Pharmacokinetic Research Group. He is currently a Doctoral candidate at the University of Maryland School of Pharmacy. His research interests include applying quantitative approaches, particularly pharmacometric techniques such as non-compartmental analysis (NCA), population pharmacokinetics (popPK), pharmacokinetics/pharmacodynamics (PK/PD), physiologically based pharmacokinetic (PBPK) modeling, and clinical trial simulations (CTS), to address critical questions in clinical practice and drug development.

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[Webinar Series] Causal Models to Support Better Decisions in Drug Development: PBPK and QSP

25 February 2025

When: Mar 4, 2025 2:00PM CETRegister here “Causal Models to Support Better Decisions in Drug Development: PBPK and QSP” Models used for decisions-making in pharmaceutical development have been limited by a bias towards small, statistically feasible models applied to small (e.g. a single trial) datasets.  This approach ignores petabytes of relevant biological and physiological data.  Additionally, statistical inferences can only be derived for the population tested.  Over the past twenty years or so, causal (mechanistic) models have been increasingly applied to leverage these data to support better decisions, especially where predictions must be made of experiments and trials not yet done.  In this talk from Jim Bosley, PhD, we cover a brief history of the field and will use Physiologicaly Based PharmacoKinetic (PBPK) and Quantitative Systems Pharmacology (QSP) examples to illustrate why such models support better and more effective drug development decisions. About the Speaker Jim Bosley, PhD Jim has spent over 20 years advancing systems biology modeling and advocating its adoption in pharmaceutical research. Prior to joining Nova In Silico he founded and ran a systems biology modeling consulting company, Clermont, Bosley LLC, serving major pharma/biotech. Prior to this, Jim started the modeling practice at Rosa & Co. building the group from one to ten principals, with the title of Vice President of Modeling and Simulation.  We was Sr. Director of Software Products for Pharsight (now a Certara company), as a Consulting Engineer for Entelos and as a Senior Engineer in DuPont’s BioChemical Science and Engineering group. He has written several articles

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