[Review Article] Cross-disciplinary mathematical modelling to benefit healthcare – could clinical pharmacology play an enabling role?
In December 2023, Stellenbosch University, Fundisa African Academy of Medicines Development and Pharmacometrics Africa convened a virtual cross-disciplinary symposium to discuss concepts of mathematical modelling applied in various interrelated scientific fields, including the science of pharmacometrics. Experts from different fields were invited to share their insights for a deeper understanding of the application, experiences, challenges and foresight of mathematical modelling in their fields. The goal was to provide an opportunity to highlight the current interlinks amongst the disciplines and possible avenues/collaborations for future research and applications. To highlight and share what we learned, a review article was just published in the British Journal of Clinical Pharmacology – you can read a copy at this link. Abstract: Clinical pharmacology is often the nexus in any cross-disciplinary team that is seeking solutions for human healthcare issues. The use and application of real-world data and artificial intelligence to better understand our ecosystem has influenced our view at the world and how we do things. This has resulted in remarkable advancements in the healthcare space and development of personalized medicines with great attributes from the application of models and simulations, contributing to a more efficient healthcare development process. A cross-disciplinary symposium was held in December 2023, whereby experts from different scientific disciplines engaged in a high-level discussion on the opportunities and challenges of mathematical models in different fields, possible future developments and decision making. A strong interlink amongst the disciplines represented was apparent, with clinical pharmacology identified as the one which integrates various scientific