Paolo Denti, PhD

Chief Scientific Officer

Paolo Denti is a professor of pharmacometrics in the Division of Clinical Pharmacology at the University of Cape Town. His work focuses mainly on tuberculosis, HIV, and malaria and involves the use of mathematical models to characterize the relationship between drug dose, concentration, and response, while quantifying the effect of patient characteristics, trial information, and other factors on this relationship. Overall, he aims to achieve quantitative understanding how of how these drugs work, so that we can suggest dose adjustments for treatment optimization and individualization, particularly needed for neglected populations, such as paediatrics and pregnancy.