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Registration now open: Physiologically Based Pharmacokinetic (PBPK) Modelling and its Applications in Maternal and Child Health

25 August 2026

Open in-person SymposiumDate: Wednesday, 28th October 2026 Venue: Biomedical Research Institute, Stellenbosch University, Cape Town, South Africa Bringing together researchers, clinicians, pharmacometricians, regulators, and industry partners to advance physiologically based pharmacokinetic (PBPK) modelling in maternal and child health across Africa. Attend a free in-person symposium exploring priorities for integrating PBPK modelling into research, clinical trials, and medicine development. Everyone with an interest in PBPK modelling and maternal and child health is welcome. Places are limited — secure your place early. For admin enquiries please contact kelly.turton@certara.com or veshni@sun.ac.za 29-30 October – Hands-on Simcyp Workshop Participate in an interactive Simcyp training workshop led by Certara. These sessions are intended for students and participants who already have access to Simcyp software. The workshop will focus on building practical PBPK modelling skills while collaboratively developing a regional capacity-building framework and roadmap for model-informed drug development across sub-Saharan Africa.

Egypt Chapter Activities Update: Helping to advance Pharmacometrics Across the Region

15 August 2026

We are pleased to share two recent engagements representing the PMX Africa Egypt Chapter in scientific and academic forums across Egypt. Vaccine Innovation Forum Dr. Nada Elhofy represented our chapter in a lecture on the role of “Model-Informed Drug Development (MIDD) in advancing vaccine innovation” (April 2026) as part of Africa CDC’s “Industrial Workshop in Vaccine Manufacturing” in collaboration with VACSERA . The session addressed how quantitative modelling and simulation can streamline vaccine research and development, optimise dosing strategies, and support clinical decision-making, bringing a pharmacometrics perspective to one of the most critical areas of public health. We extend our sincere gratitude to VACSERA, Africa CDC, and Future University in Egypt (FUE) for hosting this important event and for fostering collaboration around regional health solutions. MESPET 2026 — Bibliotheca Alexandrina, Alexandria (May 3–4, 2026) Dr. Aya Ismail represented our chapter at the 1st Annual Conference of the Middle East Society of Pharmacology and Experimental Therapeutics (MESPET), held at the Bibliotheca Alexandrina, Alexandria, Egypt (May 3–4, 2026). Dr. Ismail delivered a session titled “From Animals to Humans: Modelling as a Bridge in Drug Development,” addressing the role of quantitative modelling and simulation as a translational tool in drug development, bridging preclinical findings with clinical decision-making. In addition, Dr. Ibrahim Komeil represented the chapter by presenting a poster on Virtual Bioequivalence, highlighting the application of modelling and simulation approaches to support bioequivalence assessment and facilitate more efficient drug development. We extend our sincere gratitude to MESPET, ASPET, and Alamein International University for

Building Pharmacometrics Capacity in Africa: Inside the Egypt Chapter’s First Clinical Pharmacology & Pharmacometrics Course

6 August 2026

This July, the PMX Africa – Egypt Chapter ran its first Clinical Pharmacology & Pharmacometrics Course, delivered in partnership with the Faculty of Pharmacy at Future University in Egypt (FUE), and sponsored by DAF. What began as an idea to make quantitative pharmacology more accessible across the region turned into a two-weekend programme that reached hundreds of learners across four continents—and, by every measure we tracked, left them wanting more. A hybrid design, built for reach and depth The course was structured in two parts so it could do two things at once: reach broadly and go deep. Weekend 1 (10–11 July, online) was open to all accepted participants and covered the foundations: from the pharmacokinetics of absorption, distribution and elimination, through dosing at steady state, non-compartmental analysis and bioequivalence, pharmacodynamics, regression analysis, and a first introduction to population PK modeling. Weekend 2 (17–18 July, onsite at FUE) was an intensive, hands-on lab for a smaller hybrid track cohort, working directly in R: exploratory data analysis, NCA, population PK model building with nlmixr2, R Shiny, and interpreting model outputs. The idea was simple: give everyone a strong conceptual grounding online, then give a committed group the chance to put a keyboard under their hands and actually build models. Registration was open for just two weeks in June and drew 388 applications from across Africa, the Middle East, South Asia and beyond. After review, 312 applicants were accepted, and online attendees joined live from 26 countries, with Egypt, India, Nigeria, South

My First PAGE Experience: Learning, Sharing, and Connecting Through Pharmacometrics

31 July 2026

My name is Aya Ismail, and I am a clinical pharmacologist based in Cairo, Egypt, working in the field of clinical research and one of the co-founders of the Pharmacometrics Africa Egypt Chapter. I was also a fellow in the Advanced Pharmacometrics Training (APT) 2025 cohort. In 2026, I had the opportunity to travel to Croatia with my colleague Allan Kengo to present our work at the Population Approach Group Europe (PAGE) 2026 conference. Attending the PAGE 2026 conference was a very special experience for me, as it was my first time attending. For the first time, I was not simply following discussions about PAGE, reading its abstracts, or hearing about the incredible scientific exchanges taking place within the pharmacometrics community. I was actually there surrounded by scientists whose work had inspired my own journey into pharmacometrics. As someone coming from Egypt and growing within the African pharmacometrics community, this experience felt particularly meaningful. For me, the experience was made even more meaningful by the opportunity to present our project as part of the APT 2025 cohort. With my colleague Allan Kengo, we presented our work as a poster, sharing the project we had developed throughout the fellowship. You can view our poster here. This opportunity was made possible through the support and funding of Medicines for Malaria Venture (MMV), which enabled us to attend PAGE and present our work. I am particularly grateful to Robin Eriksson from MMV and Wynand Smythe from Certara for their supervision and guidance throughout the

Applications CLOSED: PhM-2026 Online Pharmacometrics Course

17 July 2026

New applications are closed – thank you for your interest Thank you for your interest in the course – we have had unprecedented interest in the course and, as a result, a significant backlog of emails and acceptance letters to process. We thank you in advance for your patience. Call for applications Pharmacometrics Africa Africa invites applications for PhM-2026, a supported online pharmacometrics course delivered through the PMXAfrica Moodle platform. About this series PhM-2026 builds on the PMXAfrica self-paced pharmacometrics course and will run as a structured 12-week cohort with induction, weekly lessons, live tutorials, discussion forums, progress tracking, and completion certificates. Who should apply: The course is intended for researchers, clinicians, pharmacists, pharmacologists, statisticians, data scientists, regulators, postgraduate students, and early-career scientists who want to build foundational understanding of pharmacometrics and its applications in clinical pharmacology, drug development, therapeutic optimisation, and regulatory science. Applicants should be able to commit approximately 4-6 hours per week for self-study, exercises, tutorials, and discussion. Course content: The course covers core principles of pharmacometrics, pharmacokinetics, pharmacology, biostatistics, compartmental modelling, repeated dosing, PK-PD modelling, data analysis, non-compartmental analysis, and bioequivalence. Delivery Platform and Support: The course will be delivered through PMX Africa Moodle. Accepted participants will receive Moodle access instructions before induction. Moodle support: elearning@pmxafrica.org Application Requirements: Applicants are required to have: Certification: Participants who meet the PhM-2026 completion criteria will receive a certificate of completion from Pharmacometrics Africa. Cost: Free

Egypt Joins the Pharmacometrics Africa Network

2 June 2026

We are proud to announce the official launch of the Egypt Pharmacometrics Chapter, a dedicated community of scientists, clinicians, and educators committed to advancing clinical pharmacology and model-informed drug development (MIDD) across Egypt, the Middle East, and Africa. Egypt now formally joins a growing continental network of national pharmacometrics chapters, united in the conviction that quantitative science can meaningfully transform the way medicines are developed, evaluated, and personalised for patients. The Egypt Pharmacometrics Chapter is part of the Pharmacometrics Africa network. We bring together researchers, clinical pharmacologists, pharmaceutical scientists, and educators from across Egypt who share a common ambition: to build a rigorous, inclusive, and impact-driven pharmacometrics community that can hold its own on the world stage. Our work is grounded in science and driven by a sense of regional responsibility, the belief that Egypt, sitting at the crossroads of the Middle East and Africa, is uniquely positioned to lead. Why Pharmacometrics Matters for Egypt, the Region, and the World Drug development has never been more quantitative. Across the globe, regulators, industry, and clinical scientists are turning to model-informed approaches such as pharmacometrics, population pharmacokinetic/pharmacodynamic modelling, physiologically based pharmacokinetic modelling, and systems pharmacology to make smarter, faster, and more ethical decisions about medicines. This shift is not a trend; it is a transformation, and it carries profound implications for countries like Egypt and the broader Middle East and Africa. MIDD represents a framework that integrates mathematical and computational models throughout the entire drug development lifecycle from preclinical candidate selection and

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