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Recorded: 20 May 20254pm EAT / 3pm CEST (1h) Causal Models to Support Better Decisions in Drug Development: PBPK/QSP II About the SpeakerJim Bosley, PhD has spent over 20 years advancing systems biology modeling and advocating its adoption in pharmaceutical research. Prior to joining Nova In Silico he founded and ran a systems biology modeling consulting company, Clermont, Bosley LLC, serving major pharma/biotech. Prior to this, Jim started the modeling practice at Rosa & Co. building the group from one to ten principals, with the title of Vice President of Modeling and Simulation. We was Sr. Director of Software Products for Pharsight (now a Certara company), as a Consulting Engineer for Entelos and as a Senior Engineer in DuPont’s BioChemical Science and Engineering group. He has written several articles and book chapters on QSP modeling. Jim holds a PhD (Chem. E.) from the University of Texas at Austin, an MSc (E.E.) from the University of California-Irvine, and a BSc (Chem. E.) from the University of Wisconsin. He has taught courses, and is an affiliated faculty member, at the University of Delaware. As SVP Modeling and Simulation, Jim is supporting Nova In Silico’s expert modelers and programmers with both an understanding of the current state of the art technology, but also with innovative modeling ideas. About this series Sharing knowledge, presenting advances and discussing best practices in pharmacometrics, featuring locally-relevant case studies in application of PBPK and pop-PK Who should attend: Anyone interested in learning how pharmacometrics helps to enable safe

20 May 20254:00 PM – 5:00 PM EAT (1h) Register here About the speaker Jim Bosley, PhD has spent over 20 years advancing systems biology modeling and advocating its adoption in pharmaceutical research. Prior to joining Nova In Silico he founded and ran a systems biology modeling consulting company, Clermont, Bosley LLC, serving major pharma/biotech. Prior to this, Jim started the modeling practice at Rosa & Co. building the group from one to ten principals, with the title of Vice President of Modeling and Simulation.  We was Sr. Director of Software Products for Pharsight (now a Certara company), as a Consulting Engineer for Entelos and as a Senior Engineer in DuPont’s BioChemical Science and Engineering group. He has written several articles and book chapters on QSP modeling. Jim holds a PhD (Chem. E.) from the University of Texas at Austin, an MSc (E.E.) from the University of California-Irvine, and a BSc (Chem. E.) from the University of Wisconsin. He has taught courses, and is an affiliated faculty member, at the University of Delaware. As SVP Modeling and Simulation, Jim is supporting Nova In Silico’s expert modelers and programmers with both an understanding of the current state of the art technology, but also with innovative modeling ideas. About this series Sharing knowledge, presenting advances and discussing best practices in pharmacometrics, featuring locally-relevant case studies in application of PBPK and pop-PK Who should attend: Anyone interested in learning how pharmacometrics helps to enable safe and effective use of medication Cost: Totally Free –