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Watch: Mechanistic Absorption Modeling: Enhancing Understanding and Prediction of Drug Performance Webinar

Recorded: 8 April 20254pm EAT / 3pm CEST (1h) About the Speaker Sandra Cvijic is a full professor at the Department of Pharmaceutical Technology and Cosmetology, University in Belgrade-Faculty of Pharmacy, Serbia. She holds a PhD in Medical Sciences – Pharmacy (2011) and Specialization in Pharmaceutical Technology (2015) from the University of Belgrade-Faculty of Pharmacy. She did postdoctoral research in biopharmaceutics at Johannes Gutenberg University in Mainz, Germany (2013), and was a visiting scientist at Heinrich-Heine University, Düsseldorf, Germany (2014) and Carol Davila University of Medicine and Pharmacy, Bucharest, Romania (2018). She has authored or co-authored more than 150 publications and presentations at national and international scientific meetings. She also held several seminars and workshops on PBPK/PBBM modeling. Her research interest has to do with biopharmaceutical characterization of drugs and drug products, modeling and simulation of drug absorption and disposition, drug performance in specific populations, bioperformance dissolution testing, in vitro-in vivo correlation, formulation and characterization of oral and inhalation drugs. About this series Sharing knowledge, presenting advances and discussing best practices in pharmacometrics, featuring locally-relevant case studies in application of PBPK and pop-PK Who should attend: Anyone interested in learning how pharmacometrics helps to enable safe and effective use of medication

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Protocol Paper: Therapeutic drug monitoring for antimicrobial agents for people living with HIV (TAP)

Read the full paper here Abstract: This prospective observational study will enrol adult PLWH receiving amoxicillin, azithromycin, ciprofloxacin, rifampicin, isoniazid, or ceftriaxone. Concentrations of these antibiotics will be measured locally. TDM with dose adjustment will be performed in a subset of participants on TB treatment. Pharmacokinetic parameters will be estimated using non-linear mixed effects models.

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Perspective Paper: Appraising the visibility, relevance and impacts of clinical pharmacology

Read the full paper here Abstract: Clinical pharmacology (CP) used to be a strong medical and scientific field, but during the last three decades it seems to have lost some of its appeal. We reviewed the visibility, relevance and impact of CP and clinical pharmacologists across the globe and suggest ways to strengthen the discipline to address future pharmacotherapeutic challenges.

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Upcoming Webinar: Fundamentals of Physiologically Based Pharmacokinetic (PBPK) Modelling

Register Here Wednesday, 30 April 202514:00 West African Time Last month, we had an introduction to pharmacometrics. Join us as we continue our discussion on PBPK modelling. This webinar will cover components of PBPK models, data requirements, and an introduction to PBPK modelling softwares. Important Prerequisite: Install the PKSIM software using the provided installation instructions. About this Series The Pharmacometrics Africa (Nigeria Chapter) Webinar Series is designed to provide a structured learning experience on PBPK and Population Pharmacokinetics. The series will guide participants through fundamental concepts, model development, and real-world applications. Who Should Attend? Anyone interested in learning the fundamentals of pharmacometrics and its application in medication therapy: Academics, Researchers, Postgraduate students, and Undergraduate students.

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Exploring the fundamentals of PBPK and Population Pharmacokinetics: Nigeria Chapter March 2025 Webinar Recording

PMX Africa: Nigeria ChapterMarch 2025 Webinar Introduction to PBPK and Population Pharmacokinetics Recorded: Wednesday, March 26, 2025 This was an insightful session on Pharmacokinetic Modeling, where we explored the fundamentals of PBPK and Population Pharmacokinetics. This webinar covered key differences between these modelling approaches, their applications in drug development and clinical research, and how they enhance our understanding of drug behaviour in diverse populations. A special thank you to the speaker, Babajide Shenkoya and the 50+ participants who made this webinar a success. Stay tuned for more details about next month’s webinar! About the Speaker Babajide ShenkoyaBabajide holds a Bachelor of Pharmacy degree and a Master’s in Pharmaceutical Chemistry from Obafemi Awolowo University, where he focused on statistical and computational methods at the Translational Pharmacokinetic Research Group. He is currently a Doctoral candidate at the University of Maryland School of Pharmacy. His research interests include applying quantitative approaches, particularly pharmacometric techniques such as non-compartmental analysis (NCA), population pharmacokinetics (popPK), pharmacokinetics/pharmacodynamics (PK/PD), physiologically based pharmacokinetic (PBPK) modeling, and clinical trial simulations (CTS), to address critical questions in clinical practice and drug development. About Pharmacometrics Africa: Nigeria Chapter We are a group of scientists in Nigeria, who belong to the Pharmacometrics Africa Network, dedicated to advancing patient care through clinical pharmacology and pharmacometrics. Our mission is to optimize drug therapy and improve patient outcomes by leveraging modelling and simulation tools to understand drug behaviour and patient response by providing data-driven insights to guide treatment outcomes.

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Another year of Success: Celebrating the 2025 Graduates of the Clinical Assessors Programme

Pharmacometrics Africa, in collaboration with SAHPRA and the Department of Pharmacy and Pharmacology at the University of the Witwatersrand, marks the graduation of the fourth cohort of the Clinical Assessors Short Course — a programme designed to strengthen regulatory capacity across Africa. This 14-week certified course is part of an ongoing effort to build technical knowledge in assessment of clinical sections of regulatory dossiers. The course has a primary focus on the development of professionals working in African National Regulatory Agencies, while also welcoming private sector regulatory scientists. Accredited by Wits University, the course brings together regulators, academics, patient advocates, and industry stakeholders to promote shared understanding and practical skills in clinical assessment. The most recent cohort included participants from National Regulatory Authorities in Botswana, Ethiopia, Ghana, Kenya, Namibia, Rwanda, South Africa, Tanzania, Zambia, and Zimbabwe. Their participation reflects a growing interest across the continent in strengthening regulatory systems. “This training course has once again brought together a diverse group of regulators, academic experts, and industry professionals to engage in honest, solutions-oriented dialogue. The outcomes speak directly to better patient access and improved therapeutic interventions,” added Professor Colin Pillai, CEO of Pharmacometrics Africa. “As we mark the fourth cycle of this impactful programme, we are reminded that investing in regulatory training is an investment in patient safety. These graduates are shaping a healthier, safer future for the continent,” said Dr Boitumelo Semete-Makokotlela, CEO of SAHPRA. Professor Yahya E. Choonara of the University of the Witwatersrand emphasised, “We are proud to

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[Webinar Series: Uganda Chapter] Mechanistic Absorption Modeling: Enhancing Understanding and Prediction of Drug Performance

8 April 20254pm EAT / 3pm CEST (1h) Register here About the author Sandra Cvijic is a full professor at the Department of Pharmaceutical Technology and Cosmetology, University in Belgrade-Faculty of Pharmacy, Serbia. She holds a PhD in Medical Sciences – Pharmacy (2011) and Specialization in Pharmaceutical Technology (2015) from the University of Belgrade-Faculty of Pharmacy. She did postdoctoral research in biopharmaceutics at Johannes Gutenberg University in Mainz, Germany (2013), and was a visiting scientist at Heinrich-Heine University, Düsseldorf, Germany (2014) and Carol Davila University of Medicine and Pharmacy, Bucharest, Romania (2018). She has authored or co-authored more than 150 publications and presentations at national and international scientific meetings. She also held several seminars and workshops on PBPK/PBBM modeling. Her research interest has to do with biopharmaceutical characterization of drugs and drug products, modeling and simulation of drug absorption and disposition, drug performance in specific populations, bioperformance dissolution testing, in vitro-in vivo correlation, formulation and characterization of oral and inhalation drugs. About this series Sharing knowledge, presenting advances and discussing best practices in pharmacometrics, featuring locally-relevant case studies in application of PBPK and pop-PK Who should attend: Anyone interested in learning how pharmacometrics helps to enable safe and effective use of medication Cost: Totally Free –

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Lancement du Tunisia Chapter de Pharmacometrics Africa !

Nous sommes ravis d’annoncer la création du Tunisia Chapter de Pharmacometrics Africa, le tout premier chapitre francophone de cette communauté africaine !  La pharmacométrie joue un rôle clé dans l’optimisation des traitements médicaux grâce à des approches basées sur des modèles mathématiques et statistiques. Pourtant, cette discipline reste encore peu développée en Tunisie et dans de nombreux pays francophones. C’est pour répondre à ce besoin que nous avons décidé de créer ce chapitre ! Plus d’informations : Rejoignez-nous dès aujourd’hui !Que vous souhaitiez apprendre, contribuer ou simplement échanger, nous serions ravis de vous compter parmi nous. Contactez-nous dès maintenant et faisons avancer ensemble la pharmacométrie en Tunisie et au-delà ! English Version: We are delighted to announce the creation of the Tunisia Chapter of Pharmacometrics Africa, the very first French-speaking chapter of this African community! More Information (FR) Pharmacometrics plays a key role in optimising medical treatments using approaches based on mathematical and statistical models. However, this discipline is still underdeveloped in Tunisia and in many other French-speaking countries. It is in response to this need that we have decided to create this chapter. Join us today!Whatever your interest, whether you want to learn, contribute or simply exchange ideas, we’d love to have you on board. Contact us today and let’s work together to advance pharmacometrics in Tunisia and beyond!

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PMX Africa Nigeria Chapter announces new monthly webinar series – register today!

March 2025 Edition Introduction to PBPK and Population Pharmacokinetics Date: Wednesday, March 26, 2025Time: 2 pm WAT Join us for an insightful session on Pharmacokinetic Modeling, where we’ll explore the fundamentals of PBPK and Population Pharmacokinetics. This webinar will cover key differences between these modelling approaches, their applications in drug development and clinical research, and how they enhance our understanding of drug behaviour in diverse populations. About this SeriesThe Pharmacometrics Africa (Nigeria Chapter) Webinar Series is designed to provide a structured learning experience on PBPK and Population Pharmacokinetics. The series will guide participants through fundamental concepts, model development, and real-world applications. Who Should Attend?Anyone interested in learning the fundamentals of pharmacometrics and its application in medication therapy: Academics, Researchers, Postgraduate students, and Undergraduate students. About the Speaker Babajide ShenkoyaBabajide holds a Bachelor of Pharmacy degree and a Master’s in Pharmaceutical Chemistry from Obafemi Awolowo University, where he focused on statistical and computational methods at the Translational Pharmacokinetic Research Group. He is currently a Doctoral candidate at the University of Maryland School of Pharmacy. His research interests include applying quantitative approaches, particularly pharmacometric techniques such as non-compartmental analysis (NCA), population pharmacokinetics (popPK), pharmacokinetics/pharmacodynamics (PK/PD), physiologically based pharmacokinetic (PBPK) modeling, and clinical trial simulations (CTS), to address critical questions in clinical practice and drug development.

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All about the Applied Pharmacometrics Training (APT) Fellowship 2025

Applications Closed! The Applied Pharmacometrics Training Fellowship is a collaboration between Pharmacometrics Africa, CP+ Associates, together with several pharma industry, consulting companies and academic partners. As described in our paper in CPT:PSP, this is an intensive doctoral-level fellowship program that upskills participants to conduct regulatory quality clinical pharmacology and pharmacometrics analyses that could inform decision making. The program, built on a framework developed by Pharmacometrics Africa and Certara, is an effort to increase the application of model-based drug development in Africa. Participation in this program provides opportunities to integrate work and education while facilitating the development of an international contact network. Consisting of an intensive 24-week virtual program, complemented by 2 week-long face-to-face sessions, fellows mainly work from their home location and interact via remote technology tools. The program provides online tutorials combined with hands-on project work in cooperation with partners from industry and academia. All projects end in a publishable unit, defined as a poster at a conference and/or a peer-reviewed manuscript. The Applied Pharmacometrics Training Fellowship – Africa Region aims to build scientific and leadership capability in Africa by enhancing the skills of local scientists and by facilitating knowledge transfer to their wider scientific communities. The relationships forged between the hosts of this program and the fellows’ home institutions will further the endeavour to create next-generation medicines to ease suffering and improve quality of life for patient populations around the world. Successful participants in this program are eligible for mentorship and coaching towards employment in research centres in

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